Is the lateral septum's inhibitory influence on the amygdala mediated by GABA-ergic neurons?

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Is the lateral septum's inhibitory influence on the amygdala mediated by GABA-ergic neurons?

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dc.contributor.advisor Thomas, Earl en_US
dc.contributor.author Austin, Mason en_US
dc.date.accessioned 2007-02-28T20:31:38Z
dc.date.available 2007-02-28T20:31:38Z
dc.date.issued 2004 en_US
dc.identifier.uri http://hdl.handle.net/10066/741
dc.description.abstract Previous studies suggest that the lateral septum and amygdala are critical in the production and regulation of anxiety. The lateral septum may express its anxiolytic properties by directly inhibiting the activity of the amygdala. The present study examines whether this connection is primarily mediated by GABA-ergic neurons. Rats were fully sedated and an acute recording electrode was placed in the central nucleus of the amygdala; the lateral septum was stimulated during recording. Picrotoxin was injected intraperitoneally and recording was repeated. The interaction effect of picrotoxin and stimulation support the conclusion that GABA does play a central role in this connection. en_US
dc.description.sponsorship Haverford College. Dept. of Psychology en_US
dc.format.extent 480584 bytes en_US
dc.format.extent 91558 bytes
dc.format.mimetype application/pdf en_US
dc.format.mimetype text/plain
dc.language.iso en_US en_US
dc.rights.uri http://creativecommons.org/licenses/by-nc/3.0/us/
dc.subject.lcsh Anxiety -- Physiological aspects
dc.subject.lcsh Amygdaloid body
dc.subject.lcsh Septum (Brain)
dc.title Is the lateral septum's inhibitory influence on the amygdala mediated by GABA-ergic neurons? en_US
dc.type Thesis (B.A.) en_US


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