Determining the Cause of Increased Neurogenesis in Dominant Rodents: Dissociating the Effects of Social Hierarchies and Testosterone

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Determining the Cause of Increased Neurogenesis in Dominant Rodents: Dissociating the Effects of Social Hierarchies and Testosterone

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dc.contributor.advisor Sternberg, Wendy
dc.contributor.author Fischer, David
dc.contributor.other Posner, Jeremy
dc.contributor.other Shanin, Daniel
dc.date.accessioned 2010-07-28T18:36:32Z
dc.date.available 2010-07-28T18:36:32Z
dc.date.issued 2010
dc.identifier.uri http://hdl.handle.net/10066/4943
dc.description.abstract Dominant male rodents exhibit higher neurogenesis rates than subordinate rodents. Elevated testosterone levels lead to similar increases in neurogenesis. The current study investigated the relative contribution of testosterone versus social factors to dominance-related neurogenesis. Castrated mice were administered a high dose of testosterone (HT), a low dose (LT), or an oil vehicle (OIL). Mice were then housed individually or in groups to establish dominance hierarchies. Levels of aggression, testosterone, corticosterone and neurogenesis were assessed. While HT mice exhibited the highest testosterone levels, LT mice the most aggression, and OIL mice the most corticosterone, no neurogenesis differences were found. en
dc.description.sponsorship Haverford College. Dept. of Psychology
dc.language.iso en_US en
dc.rights.uri http://creativecommons.org/licenses/by-nc/3.0/us/
dc.subject.lcsh Developmental neurobiology
dc.subject.lcsh Social hierarchy in animals
dc.subject.lcsh Dominance (Psychology)
dc.subject.lcsh Testosterone -- Physiological effect
dc.title Determining the Cause of Increased Neurogenesis in Dominant Rodents: Dissociating the Effects of Social Hierarchies and Testosterone en
dc.type Thesis (B.A.) en


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